Methyl Balance™

Activated B vitamins + TMG


Benefits and Features

Trimethylglycine (betaine) plus active forms of folate, vitamin B12, B6, and B2 work together to support cardiovascular, neuronal and emotional health, methylation processes, and promote healthy homocysteine metabolism.

Detail Overview

Methylation is essential for cellular health, the production of hormones and neurotransmitters, and the metabolism of energy.1 Optimal B vitamin levels have been linked to improved neurological and psychological health.2 This formula contains Metafolin®, a naturally occurring, universally metabolized form of folate. By avoiding multiple enzymatic activation steps, it is directly usable by the body and provides all of the benefits of folic acid, regardless of functional or genetic differences.3 Methyl Balance™ is a unique formula that combines bioactive forms of four essential B vitamins with trimethylglycine (betaine). Vitamins B2, B6, B12, and folate are provided in active, coenzyme forms for maximal bioavailability and function.

Serving Size 1 Capsule
Amount Per Capsule % Daily Value
Riboflavin (as riboflavin 5’-phosphate) 30 mg 2,308%
Vitamin B6 (as pyridoxal 5’- phosphate) 15 mg 882%
Folate (as Metafolin®‡ calcium L-5- methyltetrahydrofolate) 1,360 mcg DFE
(800 mcg)
Vitamin B12 (as methylcobalamin) 1,000 mcg 41,667%
Betaine (trimethylglycine) 600 mg *
* Daily value not established

Other Ingredients:

Vegetarian capsule (hydroxypropyl methylcellulose, water), ascorbyl palmitate, microcrystalline cellulose, and silicon dioxide.


1.Douaud G, et al. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9523-8. 

2. Groff JL, Gropper SS, Hunt, SM. Advanced Nutrition and Human Metabolism.2nd ed. West Publishing Co., St. Paul MN, USA; 1995. 

3. Lamers Y, et al.Am J Clin Nutr. 2006 Jul;84(1):156-61

Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.

Suggested Use

Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Allergy Statement

Made without common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and sesame. Non-GMO, Vegan, No synthetic colors, or flavors.


Consult your physician If you are pregnant or nursing, or have a medical condition, or taking prescription drugs, or under the age of 18 years. KEEP OUT OF REACH OF CHILDREN.