Methyl Balance™
Activated B vitamins + TMG
Product Overview
Our Methyl Balance™ supplement features Trimethylglycine (also known as betaine) and active forms of vitamins B12, B6, B2, and folate. Together, these ingredients offer support for heart health, brain function, and mood.†
These key nutrients help maintain healthy levels of homocysteine in your blood, which is essential for keeping your heart in good shape.1
Methylation, which is vital for cellular health, hormone and neurotransmitter production, and energy metabolism2, relies heavily on these optimal levels of B vitamins, which are also linked to enhanced neurological and psychological health.3
Our Methyl Balance™ formula provides optimal levels of B vitamins in their most bioavailable forms, which is necessary for your neurological and mental health.
It features Metafolin®, a specialized form of folate readily utilized by the body, eliminating the need for complex breakdown processes. This makes Methyl Balance™ highly effective for various genetic backgrounds, enhancing support for essential body functions.
Benefits
- Promotes normal homocysteine metabolism†
- Supports mood and cognitive function†
Who Can Benefit
- Individuals who want to support their heart health
- People experiencing mood disorders
Key Features
- Improved Absorption and Bioavailability: The formula provides the active forms of vitamin B2 (riboflavin 5'-phosphate) and vitamin B6 (pyridoxal 5'-phosphate) in their coenzyme states for immediate use by the body, bypassing the need for liver conversion. This immediate availability enhances their absorption and bioavailability.
- Hypoallergenic Formula: Methyl Balance™ is a hypoallergenic product made without the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, and corn. Contains no artificial colors or flavors.
Suggested Use
- Adults: Take 1 capsule daily with food as needed or as directed by a healthcare professional.
- Children: As directed by a healthcare professional.
Storage
- Store in a cool, dry place (59°-85°F) away from direct light.
Detailed Overview
Our Methyl Balance™, equipped with Trimethylglycine (betaine) and active forms of vitamins B12, B6, B2, and folate, works synergistically to support your heart, brain, and mood.†
These nutrients effectively manage homocysteine levels in the blood, which is imperative for heart health.1
Methylation is a crucial process for cellular health, hormone and neurotransmitter production, and energy metabolism.2 Research has found that optimal levels of B vitamins are associated with improved neurological and psychological health.3
This formula includes Metafolin®, a naturally occurring, universally metabolized form of folate. This direct form of folate bypasses several enzymatic activation steps, making it immediately available for the body's use and offering all the benefits of folic acid, irrespective of functional or genetic differences.4
Methyl Balance™ uniquely combines bioactive forms of four essential B vitamins with trimethylglycine (betaine). It provides vitamins B2, B6, B12, and folate in their active coenzyme forms for maximum bioavailability and efficiency.
References
- Lu XT, Wang YN, Mo QW, et al. Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial. Eur J Nutr. 2023;62(4):1599-1610. doi:10.1007/s00394-023-03087-y
- Douaud G, Refsum H, de Jager CA, et al. Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment. Proc Natl Acad Sci U S A. 2013;110(23):9523-9528. doi:10.1073/pnas.1301816110.
- Groff JL, Gropper SS, Hunt, SM. Advanced Nutrition and Human Metabolism. 2nd ed. West Publishing Co., St. Paul MN, USA; 1995.
- Lamers Y, Prinz-Langenohl R, Brämswig S, Pietrzik K. Red blood cell folate concentrations increase more after supplementation with [6S]-5-methyltetrahydrofolate than with folic acid in women of childbearing age. Am J Clin Nutr. 2006;84(1):156-161. doi:10.1093/ajcn/84.1.156.
| Serving Size 1 Capsule | ||
| Amount Per Capsule | % Daily Value | |
|---|---|---|
| Riboflavin (as riboflavin 5’-phosphate) | 30 mg | 2,308% |
| Vitamin B6 (as pyridoxal 5’- phosphate) | 15 mg | 882% |
| Folate (as Metafolin®‡ calcium L-5- methyltetrahydrofolate) | 1,360 mcg DFE (800 mcg) |
340% |
| Vitamin B12 (as methylcobalamin) | 1,000 mcg | 41,667% |
| Betaine (trimethylglycine) | 600 mg | * |
| * Daily value not established | ||
Other Ingredients:
Vegetarian capsule (hydroxypropyl methylcellulose, water), ascorbyl palmitate, microcrystalline cellulose, and silicon dioxide.
‡ Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.
References:
1.Douaud G, et al. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9523-8.
2. Groff JL, Gropper SS, Hunt, SM. Advanced Nutrition and Human Metabolism.2nd ed. West Publishing Co., St. Paul MN, USA; 1995.
3. Lamers Y, et al.Am J Clin Nutr. 2006 Jul;84(1):156-61
Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.
Suggested Use
Adults: 1 capsule daily with food as needed or as directed by a healthcare professional. Children: As directed by a healthcare professional.
Allergy Statement
- This product is made without common allergens; milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat/gluten, soybeans, and sesame
- Methyl Balance™ does not contain synthetic colors or flavors
- Vegan
- Non-GMO
- Contact a physician if you are pregnant or nursing before taking this product.
Caution
- Methyl Balance™ should not replace any medication.
- Consult a physician if you are pregnant or nursing, have a medical condition, are taking prescription drugs, or are under 18 years old.
- Keep out of reach of children.
Methyl Balance™ is a unique nutritional supplement that combines bioactive forms of four essential B vitamins and the amino acid trimethylglycine (betaine).
It supports the body's methylation processes, which are essential for cellular health, detoxification, cardiovascular health, neurological function, and emotional well-being. The supplement also helps maintain normal homocysteine metabolism, which is crucial for cardiovascular health.†
Methyl Balance™ is suitable for individuals looking to support their methylation processes, particularly those concerned over their cardiovascular, liver, neurological, and metabolic health. It is also beneficial for people who need to manage their homocysteine levels due to genetic or lifestyle-related factors.
Healthy homocysteine metabolism is crucial for maintaining overall health, particularly in relation to cardiovascular and neurological functions. Homocysteine is a sulfur-containing amino acid produced during the metabolism of methionine, an essential amino acid obtained from dietary proteins.
The metabolism of homocysteine involves several key vitamins and enzymes, particularly those from the B-vitamin complex, including folate (vitamin B9), vitamin B6, and vitamin B12. These nutrients play significant roles in the re-methylation and transsulfuration pathways (where glutathione is made) that regulate homocysteine levels in the body.
